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Clinical trials

Psychological interventions for depression among informal caregivers of older adult populations: protocol of a systematic review and meta-analysis of randomised controlled trials

Introduction: Increased life expectancy has led to an increased demand for family members to provide informal care for their older relatives in the home. Many studies suggest informal caregivers are at greater risk of experiencing symptoms of depression. However, there is a lack of research examining the effectiveness of psychological interventions targeting these symptoms alongside clinical and methodological moderators potentially associated with intervention effectiveness.

Sun, 12/13/2020 - 17:14

Ensemble programme for early intervention in informal caregivers of psychiatric adult patients: a protocol for a randomised controlled trial

Introduction: Informal caregivers play a major role in the support and maintenance of community patients with severe psychiatric disorders.

Sun, 11/29/2020 - 11:16

Dementia Family Caregivers' Willingness to Pay for an In-home Program to Reduce Behavioral Symptoms and Caregiver Stress

Objectives: Our objective was to determine whether family caregivers of people with dementia (PwD) are willing to pay for an in-home intervention that provides strategies to manage behavioral symptoms and caregiver stress and to identify predictors of willingness-to-pay (WTP).; Methods: During baseline interviews of a randomized trial and before treatment assignment, caregivers were asked how much they were willing to pay per session for an eight-session program over 3 months.

Wed, 06/19/2019 - 09:55

Comparative Effectiveness of 2 Interventions for Hispanic Caregivers of Persons with Dementia

Objectives: To compare the effectiveness of 2 caregiver interventions with known efficacy: the Resources for Enhancing Caregiver Health‐Offering Useful Treatment (REACH‐OUT) and the New York University Caregiver Intervention (NYUCI). Design: 1:1 randomized pragmatic trial. Setting: New York City. Participants: Informal Hispanic caregivers of persons with dementia (N=221; mean age 58.2, 82.8% female, 63.3% adult children, 31.7% spouses).

Thu, 05/30/2019 - 16:30

A randomized controlled trial of a hospital at home service for the terminally ill

This study evaluated the impact of a Cambridge hospital at home service (CHAH) on patients' quality of care, likelihood of remaining at home in their final 2 weeks of life and general practitioner (GP) visits. The design was a randomized controlled trial, comparing CHAH with standard care. The patient's district nurse, GP and informal carer were surveyed within 6 weeks of patient's death, and 225 district nurses, 194 GPs and 144 informal carers of 229 patients responded. There was no clear evidence that CHAH increased likelihood of remaining at home during the final 2 weeks of life.

Thu, 07/20/2017 - 15:24

Which outcomes should we measure in adult epilepsy trials? The views of people with epilepsy and informal carers

Objective: So that informed treatment decisions can be made, clinical trials need to evaluate treatments against domains that are important to people with epilepsy (PWE), their carers, and clinicians. Health professionals have identified domains of importance to them via the International League Against Epilepsy's Commission on Outcome Measurement (COME). However, patients and carers have not been systematically asked.

Thu, 07/20/2017 - 15:23

Commentary

The article reports on the results of a study showing that cholinesterase inhibitors provide little benefits for informal carers of community dwelling people with Alzheimer's disease. Cholinesterase inhibitors increase synaptic levels of acetylcholine and produce modest improvements in symptoms in clinical trials.

Thu, 07/20/2017 - 15:21

Review: cholinesterase inhibitors reduce burden and care time for informal carers of people with Alzheimer's disease

The article reports on the results of a study showing that cholinesterase inhibitors provide little benefits for informal carers of community dwelling people with Alzheimer's disease. In future Alzheimer's disease clinical trials, carer specific outcomes should be included to investigate the effects of cholinesterase inhibitors.

Thu, 07/20/2017 - 15:11