Background Prevalence of pre-menstrual syndrome (PMS) may be higher in women with Down syndrome due to syndrome specific characteristics in biochemistry, psychopathology and lifestyle. Recognition of PMS may be difficult for women with intellectual disabilities and their carers.
Method A daily diary, used to diagnose PMS with typical women, was adapted. Following its validation, the diary was completed by 33 women with Down syndrome, then adapted, and completed by a further 32 women with Down syndrome/carers.