Providing care to a partner with cancer can have a significant impact on a carer’s well-being and experience of subjectivity. However, there is little research examining how men experience the role of cancer carer, and in particular, how they negotiate constructions of gender in this role. This paper draws on a single case study of a heterosexual man caring for his partner, and conducts a narrative analysis of the construction and performance of masculine subjectivity. It was found that rather than inhabiting a stable masculinity, this carer engaged in a complex negotiation of masculinities, enacting a caring role associated with victimisation, rejection, distress and powerlessness, as well as strength and heroic resilience. We highlight the importance of the relationship context to the experience of caring, and suggest that research into the gendered experience of cancer care needs to acknowledge the active negotiation of masculinities and caring. We also discuss the utility of case study research in analyses of masculinity and cancer care, and in health psychology more broadly.