Family conflict and estrangement can complicate caregiving tasks later in life. Research suggests that adult children who are estranged do not visit their parents when their parents are sick, despite societal pressures to reconcile and take care of them. Parents also report feeling surprised that their estranged children did not return home when they were in need, which ultimately solidified the estrangement. This article offers a broad discussion of the existing research on family conflict and caregiving, then focuses more specifically on family estrangement.