Background: Supportive interventions are needed for the family and carers of people with multiple sclerosis. Methods: A rapid realist review and realist evaluation explored what helps, who it helps, when and how. Literature analysis was synthesised with a thematic analysis of qualitative interviews and focus groups with 49 family and carers of people with multiple sclerosis. Results: The resulting model summarised a family of interventions that could help people develop their capabilities and expand their resources, resulting in more positive outcomes. Conclusions: This may prevent or delay a 'tipping point' where capacity to care is overwhelmed by caring roles.