Objective: This study aimed to evaluate caregiver burden among caregivers of acute stroke patients with a biopsychosocial perspective in a Turkey sample. Methods: 72 stroke patients and 72 their caregivers were included the study. The mean age of the stroke patients included in the study was 65 +/- 12.39. The mean age of caregivers was 44.5 +/- 14 and 66.7% of them were females. Modified Motor Assessment Scale (MMAS), Standardized Mini Mental State Examination (SMMSE) and The Barthel Index (BI) were used to assess the patients with stroke.