Background: Dementia is a neurodegenerative disease that requires the accompaniment of a caregiver who is in charge of assisting and supervising basic and psychosocial needs. Objectives: The objective of this article was to determine the influence of the caregiver on the cognitive and functional decline of patients with dementia. Methods: The method was a systematic review by searching the Scopus, Pubmed and Science Direct databases between the years 2010-2020.