Aims and Objectives: To evaluate caregiver burden and factors that influence this burden among caregivers and patients with Alzheimer's disease in China.; Background: Long-term care can reduce the quality of life for caregivers and result in both mental and physical exhaustion. However, little is known about caregiver burden and associated factors in China.; Design: The study had a quantitative cross-sectional design.; Methods: A total of 309 caregivers and their patients were included in the study.