Objective: To evaluate the association between brain structural markers and caregiving strain among older informal caregivers.; Design: A secondary data analysis combining data from the Caregiver Health Effects Study (1993-1994) and the Cardiovascular Health Study MRI examination (1992-1994).; Setting: Four United States communities.; Participants: Co-residing spousal caregivers (N = 237; mean age: 76.2 years, SD: 2.2 years).; Measurements: Visually rated ventricular and white matter (WM) grades from magnet
