The purpose of this study was to determine the predictive and associative factors of the carer's general well-being, specifically concerning carers offering support to those diagnosed with Progressive Supranuclear Palsy (PSP). Results showed that the sole predictive factor of the carers general well-being were the difficulties perceived with behavioural change and cognitive status within the PSP person. Several factors were also identified as significantly associated with the carers general well-being (gender of carer, PSP persons degeneration of motor functions, perceived difficulties relating to basic and instrumental activities conducted for the PSP person and perceived difficulties relating to basic and instrumental activities conducted for the PSP person and perceived difficulties with social network). However, all factors were not significant predictor's of the PSP person's general well-being when received difficulties with behaviour change and cognitive status were included in the model. [Book abstract]