Objective: The study's main purpose has been to verify the profile of musculoskeletal disorders, emotional burden and health profile of caregivers of people bearing central nervous system injury sequelae. Methods: It is a descriptive study with 23 participating caregivers. There were applied musculoskeletal injury tests (Nordic Musculoskeletal Questionnaire), overload tests (Caregiver Burden Scale) and the Physical Mobility and Transfer Risk Assessment Scale.