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Advanced chronic obstructive pulmonary disease: More than a lung disease

Chronic obstructive pulmonary disease (COPD) is unique among leading causes of death in Western society. While the impact of other major diseases are on the decline, the prevalence, associated morbidity and attributable mortality of COPD continue to rise. The emotional burdens to patients and care-givers and financial burdens of COPD to our healthcare system are substantial. The traditional biomedical approach to COPD is failing with its focus on the underlying pathophysiology, and treatment of acute exacerbations.

Thu, 07/20/2017 - 15:10

Experiences of adults providing care to a partner or relative with depression: A meta-ethnographic synthesis

Background: International interest in the informal carer role has grown in part because of the relationship between caring and caregiver burden. It has been suggested that living with someone with depression is comparable to that of other serious mental health problems, such as schizophrenia or dementia.

Methods: This meta-ethnography included 15 studies exploring experiences of living with a relative or partner with depression. Studies were heterogeneous regarding types of relationship with the depressed individual.

Thu, 07/20/2017 - 15:10

Donepezil for dementia due to Alzheimer's disease

Background: Alzheimer's disease is the most common cause of dementia in older people. One of the aims of therapy is to inhibit the breakdown of a chemical neurotransmitter, acetylcholine, by blocking the relevant enzyme. This can be done by a group of chemicals known as cholinesterase inhibitors. Objectives: The objective of this review is to assess whether donepezil improves the well-being of patients with dementia due to Alzheimer's disease.

Thu, 07/20/2017 - 15:08

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