Healthcare in the UK is a fast-paced sector subject to ongoing change and transformation. Current focus has largely been on the recruitment and training of new nurses. However, more recently we have also seen increased recognition of the importance of Non-Medical Prescribing and Advanced Clinical Practice roles for the future of the healthcare workforce. Both Non-Medical Prescribing and Advanced Clinical Practice have been highlighted in the 2019 NHS Long Term Plan and 2020/21People Plan as key to workforce transformation and improving care. Here, we explain more about these roles and the contribution that these highly trained healthcare professionals make within multidisciplinary healthcare teams.